Primary Antibody Matched Pairs
Mouse IL6ST ELISA Pair Set 15PP (Sino Biological)
Each vial contains 60 ng of recombinant mouse IL6ST. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 750 pg/mL is recommended.
ABclonal Technology PROS1 Rabbit pAb
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
Medchemexpress LLC Recombinant human aldo-keto reductase AKR1C2, His-tagged | >90.0% | 50 UG
Recombinant human AKR1C2 protein, His-tagged, expressed in E. coli and supplied lyophilized for research use. The enzyme reduces ketosteroids using NADH/NADPH and is characterized for activity, purity, and storage stability.
- Supplied as 50 μg lyophilized protein.
- N-terminal 6xHis tag for purification and detection.
- Expressed in E. coli expression system.
- Purity >90% by reducing SDS-PAGE.
- Approximate molecular weight 38 kDa.
- Specific activity 54.55 pmol/min/μg (S-1-indanol, NADP+).
- Lyophilized from 50 mM Tris-HCl, 300 mM NaCl, pH 7.4; store -20°C.
- After reconstitution, stable at 4°C for 1 week or -20°C for longer with carrier protein.
ABclonal Technology CDC123 Rabbit pAb
Predicted to be involved in eukaryotic translation initiation factor 2 complex assembly and positive regulation of translational initiation. Located in cytoplasm.
![ABclonal Technology [KO Validated] PDK1/PDPK1 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000109506.jpg-250.jpg)
ABclonal Technology [KO Validated] PDK1/PDPK1 Rabbit pAb
Enables 3-phosphoinositide-dependent protein kinase activity, phospholipase activator activity, and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway, regulation of protein kinase activity, and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection, cytosol, and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
ABclonal Technology S100A7/Psoriasin Rabbit mAb
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs S100 proteins are localized in the cytoplasm and or nucleus of a wide range of cells and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation S100 genes include at least 13 members which are located as a cluster on chromosome 1q21 This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus The protein is overexpressed in hyperproliferative skin diseases exhibits antimicrobial activities against bacteria and induces immunomodulatory activities
ABclonal Technology Legumain (LGMN) Rabbit pAb
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.
American Research Products Inc Anti IL1B IL1F2 DLX2323
Anti-Human IL1B/IL1F2 (DLX2323) Research Grade
ABclonal Technology VDR Rabbit mAb
This gene encodes vitamin D3 receptor which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors This receptor also functions as a receptor for the secondary bile acid lithocholic acid Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism though this receptor regulates a variety of other metabolic pathways such as those involved in immune response and cancer Mutations in this gene are associated with type II vitamin D-resistant rickets A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream Alternatively spliced transcript variants encoding different isoforms have been described for this gene A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon
ABclonal Technology BOULE/BOLL Rabbit mAb
This gene belongs to the DAZ gene family required for germ cell development It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like) Loss of this gene function results in the absence of sperm in semen (azoospermia) Histological studies demonstrated that the primary defect is at the meiotic G2 M transition Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene
ABclonal Technology PIM2 Rabbit mAb
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.
ABclonal Technology CD10/MME Rabbit mAb
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL) The encoded protein is present on leukemic cells of pre-B phenotype which represent 85% of cases of ALL This protein is not restricted to leukemic cells however and is found on a variety of normal tissues The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon enkephalins substance P neurotensin oxytocin and bradykinin
ABclonal Technology TRIM21/SS-A Rabbit pAb
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
ABclonal Technology TRIM21/SS-A Rabbit pAb
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
AdipoGen RELM-beta (human) Matched Pair Detection Set (1 Set)
Matched Pair Detection Set. Detects human RELM-beta. Does not cross-react with human adiponectin, mouse adiponectin, human RBP4, human Nampt, human vaspin, human GPX3, human ANGPTL3, human progranulin, human leptin, human resistin, human IL-33, human sirtuin 1, human clusterin, mouse resistin, human FABP4. Colorimetric assay. Sample Types: . Range: 0.016 to 1ng/ml. Sensitivity: 10pg/ml. RELM-beta has been suggested to play a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELM-beta is highly homologous to that of the adipose-derived cytokine resistin. The specific and sensitive RELM-beta Matched Pair Detection Set might detect RELM-beta in serum of gut-inflamed patients. Natural levels of RELM-beta were seen in stool, but were not detectable in the serum or other cell culture models of healthy human patients. Further testing are ongoing.